Includes bibliographies and index.
|Statement||editors M. Seligmann, J.L. Preud"homme, F.M. Kourilsky.|
|Series||INSERM symposia / Institut national de la santé et de la recherche médicale -- no.1, INSERM symposia (Institut national de la santé et de la recherche médicale) -- no.1.|
|Contributions||Seligmann, M., Preud"homme, J. L., Kourilsky, F. M.|
|The Physical Object|
|Number of Pages||475|
|ISBN 10||0720445280, 0444109242|
Lymphocyte antigen receptors, in the form of immunoglobulins on B cells and T-cell receptors on T cells, are the means by which lymphocytes sense the presence of antigens in their environment. The receptors produced by each lymphocyte have a unique antigen specificity, which is determined by the structure of their antigen-binding site, as described in Chapter springhigheredcio.com by: As already reviewed, most ligands responsible for cell-cell signaling (including neurotransmitters, peptide hormones, and growth factors) bind to receptors on the surface of their target cells. Consequently, a major challenge in understanding cell-cell signaling is unraveling the mechanisms by which cell surface receptors transmit the signals initiated by ligand springhigheredcio.com: Geoffrey M Cooper. Learn lymphocyte receptors with free interactive flashcards. Choose from different sets of lymphocyte receptors flashcards on Quizlet. Start studying UVM CMB 3 Cell Surface Membrane Receptors. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
The absence of cell membrane receptors, functional or structural defects in receptor proteins, and the presence of humoral receptor antibodies account for a number of pathologic conditions. 2 Type II diabetes mellitus is a common example of hormone resistance, resulting from decreased insulin receptor number and genetic defects in the. Membrane receptors of lymphocytes: proceedings of the International Symposium on Membrane Receptors of Lymphocytes, held in Paris, May, In some cases, ligand binding induces the pinocytosis of the ligand-receptor complex. Some functional implications of the fluid nature of the lymphocyte plasma membrane are discussed. INTRODUCTION It is probable that more is known about the plasma membrane Cited by: 2. Receptors bind (attach) to specialised molecules. If the receptor has this molecule, it is activated, but if it does not it is deactivated. Depending on its state, a change inside the cell happens. Cell surface receptors (membrane receptors, transmembrane receptors) take part in communication between the cell and the outside world.
Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune springhigheredcio.com are germline-encoded host sensors, which detect molecules typical for the pathogens. They are proteins expressed, mainly, by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils and epithelial cells, to identify two classes of molecules. receptor [re-sep´tor] 1. a molecule on the cell surface (cell-surface or membrane receptor) or within a cell, usually in its nucleus (nuclear receptor) that recognizes and binds with specific molecules, producing some effect in the cell; e.g., the cell-surface receptors of immunocompetent cells that recognize antigens, complement components, or. When lymphocytes mature, they become immunocompetent, or capable of binding with a specific antigen. An immunocompetent lymphocyte displays unique proteins on its plasma membrane that act as antigen receptors. Because all of the antigen receptors of an individual lymphocyte are identical, only a specific antigen can bind to an individual. The TCR comes from the same receptor family as the antibodies IgD and IgM, the antigen receptors on the B cell membrane surface, and thus shares common structural elements. Similar to antibodies, the TCR has a variable region and a constant region, and the variable region provides the antigen-binding site (Figure ).